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DDX6 Antibody

Product Specifications

Background

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX6 encodes a DEAD box protein. It may contribute to the cell proliferation and carcinogenesis.

NCBI Gene ID

1656

Swiss Prot

P26196

Accession Number

NP_004388

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DDX6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DDX6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

52 kDa

Applications Notes

DDX6 antibody can be used for detection of DDX6 by ELISA at 1:312500. DDX6 antibody can be used for detection of DDX6 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

DDX6

NCBI Official Name

DEAD (Asp-Glu-Ala-Asp) box helicase 6

NCBI Organism

Homo sapiens

Background Reference 01

Miyaji, K., et al., (2003) J. Viral Hepat. 10 (4), 241-248.

Other Product Names

DDX6, P54, RCK, HLR2

Tested Applications

ELISA, WB

Protein ID

164664518

Physical Properties

Liquid

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