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KCNQ1 Antibody

Product Specifications

Background

KCNQ1 encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in KCNQ1 are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation.

NCBI Gene ID

3784

Swiss Prot

P51787-2

Accession Number

NP_861463

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNQ1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Cancer, Signal Transduction

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KCNQ1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=28-307

Calculated Molecular Weight

60 kDa

Applications Notes

KCNQ1 antibody can be used for detection of KCNQ1 by ELISA at 1:62500. KCNQ1 antibody can be used for detection of KCNQ1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

KCNQ1

NCBI Official Name

Potassium voltage-gated channel, KQT-like subfamily, member 1

NCBI Organism

Homo sapiens

Background Reference 01

Du, LP., et al., (2005) Biochem Biophys Res Commun. 332 (3), 677-87.

Other Product Names

KCNQ1, LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1

Tested Applications

ELISA, WB

Protein ID

32479525

Physical Properties

Liquid

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