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CLCN3 Antibody

Product Specifications

Background

CLCN3 plays an important role in the cell proliferation of vascular smooth muscle cells. The PDZ-binding isoform of CLCN3 resides in the Golgi where it co-localizes with a small amount of CFTR (cystic fibrosis transmembrane conductance regulator) .

NCBI Gene ID

1182

Swiss Prot

P51790

Accession Number

NP_776297

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLCN3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CLCN3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

95 kDa

Applications Notes

CLCN3 antibody can be used for detection of CLCN3 by ELISA at 1:1562500. CLCN3 antibody can be used for detection of CLCN3 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CLCN3

NCBI Official Name

Chloride channel, voltage-sensitive 3

NCBI Organism

Homo sapiens

Background Reference 01

Salazar, G., et al., (2004) J. Biol. Chem. 279 (24), 25430-25439.

Other Product Names

CLCN3, CLC3, ClC-3

Tested Applications

ELISA, WB, IHC

Protein ID

55770840

Physical Properties

Liquid

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