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KCNH6 Antibody

Product Specifications

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

NCBI Gene ID

81033

Swiss Prot

Q9H252

Accession Number

NP_110406

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNH6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KCNH6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

109 kDa, 100 kDa

Applications Notes

KCNH6 antibody can be used for detection of KCNH6 by ELISA at 1:12500. KCNH6 antibody can be used for detection of KCNH6 by western blot at 2.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

KCNH6

NCBI Official Name

Potassium voltage-gated channel, subfamily H (eag-related), member 6

NCBI Organism

Homo sapiens

Background Reference 01

Bauer, C.K., et al., (2003) Pflugers Arch. 445 (5), 589-600.

Other Product Names

KCNH6, ERG2, ERG-2, HERG2, Kv11.2, hERG-2

Tested Applications

ELISA, WB

Protein ID

13540549

Physical Properties

Liquid

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