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P2RX2 Antibody

Product Specifications

Background

P2RX2 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.

NCBI Gene ID

22953

Swiss Prot

Q9UBL9-5

Accession Number

NP_777361

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human P2RX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store P2RX2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

42 kDa, 44 kDa, 49 kDa, 52 kDa, 55 kDa, 45 kDa

Applications Notes

P2RX2 antibody can be used for detection of P2RX2 by ELISA at 1:312500. P2RX2 antibody can be used for detection of P2RX2 by western blot at 0.6 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

P2RX2

NCBI Official Name

Purinergic receptor P2X, ligand-gated ion channel, 2

NCBI Organism

Homo sapiens

Background Reference 01

Barrera, N.P., et al., (2005) J. Biol. Chem. 280 (11), 10759-10765.

Other Product Names

P2RX2, P2X2, DFNA41

Tested Applications

ELISA, WB, IHC

Protein ID

28416921

Physical Properties

Liquid

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