P2RXL1 Antibody
Product Specifications
Background
P2RXL1 encodes a protein in the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. P2RXL1 is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells.
NCBI Gene ID
9127
Swiss Prot
O15547
Accession Number
NP_005437
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human P2RXL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store P2RXL1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
47 kDa
Applications Notes
P2RXL1 antibody can be used for detection of P2RXL1 by ELISA at 1:312500. P2RXL1 antibody can be used for detection of P2RXL1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
P2RX6
NCBI Official Name
Purinergic receptor P2X, ligand-gated ion channel, 6
NCBI Organism
Homo sapiens
Background Reference 01
Glass, R., et al., (2002) Cell. Mol. Life Sci. 59 (5), 870-881.
Other Product Names
P2RXL1, P2X6, P2XM, P2RXL1
Tested Applications
ELISA, WB
Protein ID
157419148
Physical Properties
Liquid
Curated Selection
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