CLIon Channel1 Antibody
Product Specifications
Background
Chloride intracellular channel 1 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIon Channel1 encodes a protein that localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
NCBI Gene ID
1192
Swiss Prot
O00299
Accession Number
NP_001279
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLIon Channel1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CLIon Channel1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=28-233
Calculated Molecular Weight
27 kDa
Applications Notes
CLIon Channel1 antibody can be used for detection of CLIon Channel1 by ELISA at 1:312500. CLIon Channel1 antibody can be used for detection of CLIon Channel1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CLIC1
NCBI Official Name
Chloride intracellular channel 1
NCBI Organism
Homo sapiens
Background Reference 01
Bruneel, A., (2005) Proteomics 5 (15), 3876-3884.
Other Product Names
CLIon Channel1, G6, NCC27
Tested Applications
ELISA, WB
Protein ID
14251209
Physical Properties
Liquid
Curated Selection
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