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GRIN2C Antibody

Product Specifications

Background

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D) .

NCBI Gene ID

2905

Swiss Prot

Q14957

Accession Number

NP_000826

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GRIN2C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GRIN2C antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

136 kDa

Applications Notes

GRIN2C antibody can be used for detection of GRIN2C by ELISA at 1:62500. GRIN2C antibody can be used for detection of GRIN2C by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

GRIN2C

NCBI Official Name

Glutamate receptor, ionotropic, N-methyl D-aspartate 2C

NCBI Organism

Homo sapiens

Background Reference 01

Self, R.L., et al., (2004) Brain Res. 995 (1), 39-45.

Other Product Names

GRIN2C, NR2C, GluN2C, NMDAR2C

Tested Applications

ELISA, WB

Protein ID

55770854

Physical Properties

Liquid

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