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SCNN1B Antibody

Product Specifications

Background

When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.

NCBI Gene ID

6338

Swiss Prot

P51168

Accession Number

NP_000327

Host

Rabbit

Reactivity

Human, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCNN1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SCNN1B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

70 kDa

Applications Notes

SCNN1B antibody can be used for detection of SCNN1B by ELISA at 1:312500. SCNN1B antibody can be used for detection of SCNN1B by western blot at 0.125 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SCNN1B

NCBI Official Name

Sodium channel, non-voltage-gated 1, beta subunit

NCBI Organism

Homo sapiens

Background Reference 01

Snyder, P.M., et al., (2004) J. Biol. Chem. 279 (44), 45753-45758.

Other Product Names

SCNN1B, BESC1, ENaCb, SCNEB, ENaCbeta

Tested Applications

ELISA, WB

Protein ID

124301196

Physical Properties

Liquid

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