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CHRNA1 Antibody

Product Specifications

Background

The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 The CHRNA1 gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating.

NCBI Gene ID

1134

Swiss Prot

Q53SH4

Accession Number

NP_000070

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNA1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10408 - Fetal Kidney Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CHRNA1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

52 kDa

Applications Notes

CHRNA1 antibody can be used for detection of CHRNA1 by ELISA at 1:2500. CHRNA1 antibody can be used for detection of CHRNA1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CHRNA1

NCBI Official Name

Cholinergic receptor, nicotinic, alpha 1 (muscle)

NCBI Organism

Homo sapiens

Background Reference 01

Webster, R., et al., (2004) Neurology 62 (7), 1090-1096.

Other Product Names

CHRNA1, ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS

Tested Applications

ELISA, WB

Protein ID

4557457

Physical Properties

Liquid

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