CHRNA1 Antibody
Product Specifications
Background
The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating.
NCBI Gene ID
1134
Swiss Prot
P02708-2
Accession Number
NP_000070
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CHRNA1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
52 kDa
Applications Notes
CHRNA1 antibody can be used for detection of CHRNA1 by ELISA at 1:312500. CHRNA1 antibody can be used for detection of CHRNA1 by western blot at 1.8 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CHRNA1
NCBI Official Name
Cholinergic receptor, nicotinic, alpha 1 (muscle)
NCBI Organism
Homo sapiens
Background Reference 01
Webster, R., et al., (2004) Neurology 62 (7), 1090-1096.
Other Product Names
CHRNA1, ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
Tested Applications
ELISA, WB
Protein ID
4557457
Physical Properties
Liquid
Curated Selection
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