RRN3 Antibody
Product Specifications
Background
In mammals, growth-dependent regulation of RNA polymerase I (Pol I) transcription is mediated by RRN3, an essential initiation factor. It interacts with Pol I in the absence of template DNA, augments Pol I transcription in vivo and rescues transcription in extracts from growth-arrested cells in vitro.
NCBI Gene ID
54700
Swiss Prot
Q9NYV6
Accession Number
NP_060897
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RRN3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RRN3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=28-099
Calculated Molecular Weight
74 kDa
Applications Notes
RRN3 antibody can be used for detection of RRN3 by ELISA at 1:62500. RRN3 antibody can be used for detection of RRN3 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RRN3
NCBI Official Name
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
NCBI Organism
Homo sapiens
Background Reference 01
Miller, G., et al., (2001) EMBO J. 20 (6), 1373-1382.
Other Product Names
RRN3, TIFIA, A-270G1.2
Tested Applications
ELISA, WB
Protein ID
93102377
Physical Properties
Liquid
Curated Selection
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