VPS24 Antibody
Product Specifications
Background
VPS24 encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily.
NCBI Gene ID
51652
Swiss Prot
Q3ZTS9
Accession Number
NP_057163
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VPS24.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store VPS24 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=28-095
Calculated Molecular Weight
25 kDa
Applications Notes
VPS24 antibody can be used for detection of VPS24 by ELISA at 1:12500. VPS24 antibody can be used for detection of VPS24 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CHMP3
NCBI Official Name
Charged multivesicular body protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Whitley, P., et al., (2003) J Biol Chem. 278 (40), 38786-95.
Other Product Names
VPS24, NEDF, VPS24, CGI-149
Tested Applications
ELISA, WB
Protein ID
7706353
Physical Properties
Liquid
Curated Selection
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