COLQ Antibody
Product Specifications
Background
COLQ encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in COLQ are associated with endplate acetylcholinesterase deficiency.
NCBI Gene ID
8292
Swiss Prot
Q6DK18
Accession Number
NP_005668
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COLQ.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store COLQ antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=28-066
Calculated Molecular Weight
48 kDa
Applications Notes
COLQ antibody can be used for detection of COLQ by ELISA at 1:312500. COLQ antibody can be used for detection of COLQ by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
COLQ
NCBI Official Name
Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
NCBI Organism
Homo sapiens
Background Reference 01
Ting, A.K., et al., (2005) Chem. Biol. Interact. 157-158, 63-70.
Other Product Names
COLQ, EAD
Tested Applications
ELISA, WB
Protein ID
18105016
Physical Properties
Liquid
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