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COLQ Antibody

Product Specifications

Background

COLQ encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in COLQ are associated with endplate acetylcholinesterase deficiency.

NCBI Gene ID

8292

Swiss Prot

Q9Y215-8

Accession Number

NP_536805

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COLQ.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store COLQ antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

34 kDa

Applications Notes

COLQ antibody can be used for detection of COLQ by ELISA at 1:62500. COLQ antibody can be used for detection of COLQ by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

COLQ

NCBI Official Name

Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

NCBI Organism

Homo sapiens

Background Reference 01

Ishigaki, K., et al., (2003) Neuromuscul. Disord. 13 (3), 236-244.

Other Product Names

COLQ, EAD

Tested Applications

ELISA, WB

Protein ID

18105030

Physical Properties

Liquid

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