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SMARCB1 Antibody

Product Specifications

Background

The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors.

NCBI Gene ID

6598

Swiss Prot

Q12824

Accession Number

NP_003064

Host

Rabbit

Reactivity

Human, Mouse, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMARCB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cell Cycle, Cancer, Apoptosis

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMARCB1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=28-018

Calculated Molecular Weight

44 kDa

Applications Notes

SMARCB1 antibody can be used for detection of SMARCB1 by ELISA at 1:312500. SMARCB1 antibody can be used for detection of SMARCB1 by western blot at 2.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SMARCB1

NCBI Official Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

NCBI Organism

Homo sapiens

Background Reference 01

Mueller, W., et al., (2004) Neuropathol Appl Neurobiol 30 (3), 304-307.

Other Product Names

SMARCB1, RDT, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1

Tested Applications

ELISA, WB, IHC

Protein ID

27545326

Physical Properties

Liquid

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