UBE2N Antibody
Product Specifications
Background
UBE2N encodes a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
NCBI Gene ID
7334
Swiss Prot
P61088
Accession Number
NP_003339
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish, Drosophila
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE2N.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store UBE2N antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
17 kDa
Applications Notes
UBE2N antibody can be used for detection of UBE2N by ELISA at 1:312500. UBE2N antibody can be used for detection of UBE2N by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
UBE2N
NCBI Official Name
Ubiquitin-conjugating enzyme E2N
NCBI Organism
Homo sapiens
Background Reference 01
Bothos, J., et al., (2003) Oncogene 22 (46), 7101-7107.
Other Product Names
UBE2N, UBC13, UbcH13, HEL-S-71, UbcH-ben
Tested Applications
ELISA, WB
Protein ID
4507793
Physical Properties
Liquid
Frequently Asked Questions
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