RGS13 Antibody
Product Specifications
Background
The protein encoded by RGS13 is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown.
NCBI Gene ID
6003
Swiss Prot
O14921
Accession Number
NP_658912
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS13.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1224 - Daudi Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RGS13 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=27-990
Calculated Molecular Weight
17 kDa, 19 kDa
Applications Notes
RGS13 antibody can be used for detection of RGS13 by ELISA at 1:62500. RGS13 antibody can be used for detection of RGS13 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RGS13
NCBI Official Name
Regulator of G-protein signaling 13
NCBI Organism
Homo sapiens
Background Reference 01
Islam, T.C., et al., (2003) Leukemia 17 (9), 1880-1890.
Other Product Names
RGS13
Tested Applications
ELISA, WB
Protein ID
21464139
Physical Properties
Liquid
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