RGS13 Antibody

The protein encoded by RGS13 is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RGS13 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

RGS13 antibody can be used for detection of RGS13 by ELISA at 1:62500. RGS13 antibody can be used for detection of RGS13 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.