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ASGR2 Antibody

Product Specifications

Background

ASGR2 binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.

NCBI Gene ID

23253

Swiss Prot

P07307

Accession Number

NP_001172

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ASGR2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10410 - Fetal Lung Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ASGR2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

35 kDa

Applications Notes

ASGR2 antibody can be used for detection of ASGR2 by ELISA at 1:312500. ASGR2 antibody can be used for detection of ASGR2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ANKRD12

NCBI Official Name

Ankyrin repeat domain 12

NCBI Organism

Homo sapiens

Background Reference 01

Yik, J.H., et al., (2002) J. Biol. Chem. 277 (43), 40844-40852.

Other Product Names

ASGR2, ANCO1, GAC-1, ANCO-2, Nbla00144

Tested Applications

ELISA, WB, IHC

Protein ID

4502253

Physical Properties

Liquid

Frequently Asked Questions

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