ASGR2 Antibody
Product Specifications
Background
ASGR2 binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.
NCBI Gene ID
23253
Swiss Prot
P07307
Accession Number
NP_001172
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ASGR2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10410 - Fetal Lung Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ASGR2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
35 kDa
Applications Notes
ASGR2 antibody can be used for detection of ASGR2 by ELISA at 1:312500. ASGR2 antibody can be used for detection of ASGR2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ANKRD12
NCBI Official Name
Ankyrin repeat domain 12
NCBI Organism
Homo sapiens
Background Reference 01
Yik, J.H., et al., (2002) J. Biol. Chem. 277 (43), 40844-40852.
Other Product Names
ASGR2, ANCO1, GAC-1, ANCO-2, Nbla00144
Tested Applications
ELISA, WB, IHC
Protein ID
4502253
Physical Properties
Liquid
Curated Selection
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