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ASGR1 Antibody

Product Specifications

Background

ASGR1 is a cell surface receptor binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface.

NCBI Gene ID

432

Swiss Prot

P07306

Accession Number

NP_001662

Host

Rabbit

Reactivity

Human, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ASGR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ASGR1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

33 kDa

Applications Notes

ASGR1 antibody can be used for detection of ASGR1 by ELISA at 1:312500. ASGR1 antibody can be used for detection of ASGR1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ASGR1

NCBI Official Name

Asialoglycoprotein receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Yik, J.H. et al., (2002) J. Biol. Chem. 277 (49), 47305-47312.

Other Product Names

ASGR1, HL-1, ASGPR, ASGPR1, CLEC4H1

Tested Applications

ELISA, WB

Protein ID

4502251

Physical Properties

Liquid

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