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PARP3 Antibody

Product Specifications

Background

PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

NCBI Gene ID

10039

Swiss Prot

Q9Y6F1

Accession Number

NP_005476

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PARP3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=27-941

Calculated Molecular Weight

59 kDa, 61 kDa, 60 kDa

Applications Notes

PARP3 antibody can be used for detection of PARP3 by ELISA at 1:62500. PARP3 antibody can be used for detection of PARP3 by western blot at 1.0-2.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

PARP3

NCBI Official Name

Poly (ADP-ribose) polymerase family, member 3

NCBI Organism

Homo sapiens

Background Reference 01

Augustin, A., et al., (2003) J. Cell. Sci. 116 (Pt 8), 1551-1562.

Other Product Names

PARP3, IRT1, ARTD3, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3

Tested Applications

ELISA, WB, IHC

Protein ID

158634482

Physical Properties

Liquid

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