PARP3 Antibody
Product Specifications
Background
PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
10039
Swiss Prot
Q9Y6F1
Accession Number
NP_005476
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PARP3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
59 kDa, 61 kDa, 60 kDa
Applications Notes
PARP3 antibody can be used for detection of PARP3 by ELISA at 1:62500. PARP3 antibody can be used for detection of PARP3 by western blot at 1.0-2.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PARP3
NCBI Official Name
Poly (ADP-ribose) polymerase family, member 3
NCBI Organism
Homo sapiens
Background Reference 01
Augustin, A., et al., (2003) J. Cell. Sci. 116 (Pt 8), 1551-1562.
Other Product Names
PARP3, IRT1, ARTD3, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3
Tested Applications
ELISA, WB, IHC
Protein ID
158634482
Physical Properties
Liquid
Frequently Asked Questions
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