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PARP2 Antibody

Product Specifications

Background

PARP2 contains a catalytic domain and is capable of catalyzing a poly (ADP-ribosyl) ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of protein.

NCBI Gene ID

10038

Swiss Prot

Q9UGN5

Accession Number

NP_005475

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1207 - Raji Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PARP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

61 kDa

Applications Notes

PARP2 antibody can be used for detection of PARP2 by ELISA at 1:62500. PARP2 antibody can be used for detection of PARP2 by western blot at 1.6 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

PARP2

NCBI Official Name

Poly (ADP-ribose) polymerase 2

NCBI Organism

Homo sapiens

Background Reference 01

Malanga, M. et al., (2004) J. Biol. Chem. 279 (7), 5244-5248.

Other Product Names

PARP2, ARTD2, ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2

Tested Applications

ELISA, WB

Protein ID

110825961

Physical Properties

Liquid

Frequently Asked Questions

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