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TBX4 Antibody

Product Specifications

Background

The TBX4 gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.

NCBI Gene ID

9496

Swiss Prot

P57082

Accession Number

NP_060958

Host

Rabbit

Reactivity

Human, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TBX4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

60 kDa

Applications Notes

TBX4 antibody can be used for detection of TBX4 by ELISA at 1:62500. TBX4 antibody can be used for detection of TBX4 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TBX4

NCBI Official Name

T-box 4

NCBI Organism

Homo sapiens

Background Reference 01

Bongers, E.M., et al., (2004) Am. J. Hum. Genet. 74 (6), 1239-1248.

Other Product Names

TBX4, SPS

Tested Applications

ELISA, WB

Protein ID

18129690

Physical Properties

Liquid

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