NR1I3 Antibody

Product Specifications

Background

NR1I3 is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.

NCBI Gene ID

9970

Swiss Prot

Q5VTW5

Accession Number

NP_005113

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1I3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Signal Transduction

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR1I3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

40 kDa, 38 kDa, 32 kDa, 35 kDa, 37 kDa, 36 kDa, 33 kDa, 30 kDa, 35 kDa, 35 kDa, 38 kDa, 36 kDa, 40 kDa, 36 kDa, 40 kDa

Applications Notes

NR1I3 antibody can be used for detection of NR1I3 by ELISA at 1:62500. NR1I3 antibody can be used for detection of NR1I3 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

NR1I3

NCBI Official Name

Nuclear receptor subfamily 1, group I, member 3

NCBI Organism

Homo sapiens

Background Reference 01

Ferguson, S.S., (2005) Mol. Pharmacol. 68 (3), 747-757.

Other Product Names

NR1I3, CAR, CAR-BETA, CAR-SV1, CAR-SV10, CAR-SV11, CAR-SV12, CAR-SV13, CAR-SV14, CAR-SV15, CAR-SV17, CAR-SV18, CAR-SV19, CAR-SV20, CAR-SV21, CAR-SV4, CAR-SV6, CAR-SV7, CAR-SV8, CAR-SV9, CAR1, MB67, MGC97144