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WHSC1 Antibody

Product Specifications

Background

WHSC1 encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4.

NCBI Gene ID

7468

Swiss Prot

O96031

Accession Number

NP_055734

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WHSC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store WHSC1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

88 kDa, 69 kDa, 152 kDa, 152 kDa, 71 kDa, 71 kDa, 71 kDa, 152 kDa

Applications Notes

WHSC1 antibody can be used for detection of WHSC1 by ELISA at 1:12500. WHSC1 antibody can be used for detection of WHSC1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

WHSC1

NCBI Official Name

Wolf-Hirschhorn syndrome candidate 1

NCBI Organism

Homo sapiens

Background Reference 01

Santra, M., et al., (2003) Blood 101 (6), 2374-2376.

Other Product Names

WHSC1, WHS, NSD2, TRX5, MMSET, REIIBP

Tested Applications

ELISA, WB

Protein ID

19913346

Physical Properties

Liquid

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