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TCEA1 Antibody

Product Specifications

Background

TCEA1 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. TCEA1 has a role in suppression of transient pausing, which is the most important contribution of TCEA1 to elongation from a stall position. TCEA1 fuse to PLAG1 protein which is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors.

NCBI Gene ID

6917

Swiss Prot

P23193

Accession Number

NP_006747

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCEA1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Tranfected 293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TCEA1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

34 kDa, 32 kDa

Applications Notes

TCEA1 antibody can be used for detection of TCEA1 by ELISA at 1:312500. TCEA1 antibody can be used for detection of TCEA1 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TCEA1

NCBI Official Name

Transcription elongation factor A (SII), 1

NCBI Organism

Homo sapiens

Background Reference 01

Kimura, K., (2006) Genome Res. 16 (1), 55-65.

Other Product Names

TCEA1, SII, TCEA, TF2S, GTF2S, TFIIS

Tested Applications

ELISA, WB

Protein ID

5803191

Physical Properties

Liquid

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