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SUPT5H Antibody

Product Specifications

Background

SUPT5H and its binding partner regulate transcriptional elongation by RNA polymerase II. SPT4 and SPT5 are involved in both 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) -mediated transcriptional inhibition and the activation of transcriptional elongation by the human immunodeficiency virus type 1 (HIV-1) Tat protein.

NCBI Gene ID

6829

Swiss Prot

O00267

Accession Number

NP_003160

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SUPT5H.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cell Cycle

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SUPT5H antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

121 kDa

Applications Notes

SUPT5H antibody can be used for detection of SUPT5H by ELISA at 1:62500. SUPT5H antibody can be used for detection of SUPT5H by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SUPT5H

NCBI Official Name

Suppressor of Ty 5 homolog (S. cerevisiae)

NCBI Organism

Homo sapiens

Background Reference 01

Bourgeois, C.F., et al., (2002) Mol. Cell. Biol. 22 (4), 1079-1093.

Other Product Names

SUPT5H, SPT5, SPT5H, Tat-CT1

Tested Applications

ELISA, WB, IHC

Protein ID

20149524

Physical Properties

Liquid

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