SOX12 Antibody

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY) . Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The SOX12 gene encodes a protein that was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SOX12 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

SOX12 antibody can be used for detection of SOX12 by ELISA at 1:312500. SOX12 antibody can be used for detection of SOX12 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.