RFX4 Antibody
Product Specifications
Background
RFX4 is a transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX4 is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. RFX4 may be a transcriptional repressor rather than a transcriptional activator.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.
NCBI Gene ID
5992
Swiss Prot
Q96S80
Accession Number
NP_002911
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RFX4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RFX4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
64 kDa, 73 kDa, 83 kDa
Applications Notes
RFX4 antibody can be used for detection of RFX4 by ELISA at 1:1562500. RFX4 antibody can be used for detection of RFX4 by western blot at 5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RFX4
NCBI Official Name
Regulatory factor X, 4 (influences HLA class II expression)
NCBI Organism
Homo sapiens
Background Reference 01
Glaser, B., (2005) Mol. Psychiatry 10 (10), 920-927.
Other Product Names
RFX4, NYD-SP10
Tested Applications
ELISA, WB
Protein ID
15011898
Physical Properties
Liquid
Curated Selection
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