ENG Antibody
Product Specifications
Background
Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
NCBI Gene ID
2022
Swiss Prot
P17813
Accession Number
NP_000109
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ENG.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ENG antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
68 kDa
Applications Notes
ENG antibody can be used for detection of ENG by ELISA at 1:312500. ENG antibody can be used for detection of ENG by western blot at 2.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ENG
NCBI Official Name
Endoglin
NCBI Organism
Homo sapiens
Background Reference 01
Sanz-Rodriguez, F., et al., (2004) J. Biol. Chem. 279 (31), 32858-32868.
Other Product Names
ENG, END, HHT1, ORW1
Tested Applications
ELISA, WB, IHC
Protein ID
4557555
Physical Properties
Liquid
Frequently Asked Questions
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