TTRAP Antibody
Product Specifications
Background
The TTRAP gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
NCBI Gene ID
51567
Swiss Prot
O95551
Accession Number
NP_057698
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TTRAP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TTRAP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
41 kDa
Applications Notes
TTRAP antibody can be used for detection of TTRAP by ELISA at 1:62500. TTRAP antibody can be used for detection of TTRAP by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TDP2
NCBI Official Name
Tyrosyl-DNA phosphodiesterase 2
NCBI Organism
Homo sapiens
Background Reference 01
Pei, H., et al., (2003) Oncogene 22 (18), 2699-2709.
Other Product Names
TTRAP, EAP2, AD022, EAPII, TTRAP, hTDP2, dJ30M3.3, RP1-30M3.3
Tested Applications
ELISA, WB, IHC
Protein ID
23510348
Physical Properties
Liquid
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