PCYOX1 Antibody
Product Specifications
Background
Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.
NCBI Gene ID
51449
Swiss Prot
Q9UHG3
Accession Number
NP_057381
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCYOX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PCYOX1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=27-767
Calculated Molecular Weight
57 kDa
Applications Notes
PCYOX1 antibody can be used for detection of PCYOX1 by ELISA at 1:12500. PCYOX1 antibody can be used for detection of PCYOX1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PCYOX1
NCBI Official Name
Prenylcysteine oxidase 1
NCBI Organism
Homo sapiens
Background Reference 01
Clark, H.F., et al., (2003) Genome Res. 13 (10), 2265-2270.
Other Product Names
PCYOX1, PCL1
Tested Applications
ELISA, WB, IHC
Protein ID
166795301
Physical Properties
Liquid
Curated Selection
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