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PCYOX1 Antibody

Product Specifications

Background

Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.

NCBI Gene ID

51449

Swiss Prot

Q9UHG3

Accession Number

NP_057381

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCYOX1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PCYOX1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

57 kDa

Applications Notes

PCYOX1 antibody can be used for detection of PCYOX1 by ELISA at 1:12500. PCYOX1 antibody can be used for detection of PCYOX1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

PCYOX1

NCBI Official Name

Prenylcysteine oxidase 1

NCBI Organism

Homo sapiens

Background Reference 01

Clark, H.F., et al., (2003) Genome Res. 13 (10), 2265-2270.

Other Product Names

PCYOX1, PCL1

Tested Applications

ELISA, WB, IHC

Protein ID

166795301

Physical Properties

Liquid

Frequently Asked Questions

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