REXO4 Antibody
Product Specifications
Background
The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE) . QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
NCBI Gene ID
57109
Swiss Prot
Q9GZR2
Accession Number
NP_065118
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human REXO4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store REXO4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=27-751
Calculated Molecular Weight
47 kDa
Applications Notes
REXO4 antibody can be used for detection of REXO4 by ELISA at 1:1562500. REXO4 antibody can be used for detection of REXO4 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
REXO4
NCBI Official Name
REX4, RNA exonuclease 4 homolog (S. cerevisiae)
NCBI Organism
Homo sapiens
Background Reference 01
Montano, M.M., et al., (2000) J. Biol. Chem. 275 (44), 34306-34313.
Other Product Names
REXO4, REX4, XPMC2, XPMC2H
Tested Applications
ELISA, WB
Protein ID
76781492
Physical Properties
Liquid
Curated Selection
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