HTATIP2 Antibody
Product Specifications
Background
CC3 (HTATIP2) is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a novel serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23-H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription.
NCBI Gene ID
10553
Swiss Prot
O15383
Accession Number
NP_006401
Host
Rabbit
Reactivity
Human, Mouse, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTATIP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Apoptosis
Purification
Antibody is supplied as total IgG.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HTATIP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
27 kDa
Applications Notes
HTATIP2 antibody can be used for detection of HTATIP2 by ELISA at 1:1562500. HTATIP2 antibody can be used for detection of HTATIP2 by western blot at 0.5-1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HTATIP2
NCBI Official Name
HIV-1 Tat interactive protein 2, 30kDa
NCBI Organism
Homo sapiens
Background Reference 01
Jiang, C., et al., (2004) J.Biol.Chem.279 (26), 27781-27789.
Other Product Names
HTATIP2, CC3, TIP30, SDR44U1
Tested Applications
ELISA, WB, IHC
Protein ID
148728164
Physical Properties
Liquid
Curated Selection
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