HIon Channel1 Antibody
Product Specifications
Background
HIon Channel1 is a transcriptional repressor. HIon Channel1 may act as a tumor suppressor. HIon Channel1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIon Channel1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.
NCBI Gene ID
3090
Swiss Prot
Q14526-2
Accession Number
NP_006488
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HIon Channel1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cell Cycle, Cancer, Apoptosis
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HIon Channel1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
74 kDa
Applications Notes
HIon Channel1 antibody can be used for detection of HIon Channel1 by ELISA at 1:312500. HIon Channel1 antibody can be used for detection of HIon Channel1 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HIC1
NCBI Official Name
Hypermethylated in cancer 1
NCBI Organism
Homo sapiens
Background Reference 01
Chopin, V. (2006) Med Sci (Paris) 22 (1), 54-61.
Other Product Names
HIon Channel1, hic-1, ZBTB29, ZNF901
Tested Applications
ELISA, WB
Protein ID
61676186
Physical Properties
Liquid
Curated Selection
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