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HIon Channel1 Antibody

Product Specifications

Background

HIon Channel1 is a transcriptional repressor. HIon Channel1 may act as a tumor suppressor. HIon Channel1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIon Channel1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.

NCBI Gene ID

3090

Swiss Prot

Q14526-2

Accession Number

NP_006488

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HIon Channel1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cell Cycle, Cancer, Apoptosis

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HIon Channel1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

74 kDa

Applications Notes

HIon Channel1 antibody can be used for detection of HIon Channel1 by ELISA at 1:312500. HIon Channel1 antibody can be used for detection of HIon Channel1 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

HIC1

NCBI Official Name

Hypermethylated in cancer 1

NCBI Organism

Homo sapiens

Background Reference 01

Chopin, V. (2006) Med Sci (Paris) 22 (1), 54-61.

Other Product Names

HIon Channel1, hic-1, ZBTB29, ZNF901

Tested Applications

ELISA, WB

Protein ID

61676186

Physical Properties

Liquid

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