GRM6 Antibody
Product Specifications
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. GRM6 is part of Group III which is linked to the inhibition of the cyclic AMP cascade.
NCBI Gene ID
2916
Swiss Prot
O15303
Accession Number
NP_000834
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GRM6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cell Cycle, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GRM6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
95 kDa
Applications Notes
GRM6 antibody can be used for detection of GRM6 by ELISA at 1:62500. GRM6 antibody can be used for detection of GRM6 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GRM6
NCBI Official Name
Glutamate receptor, metabotropic 6
NCBI Organism
Homo sapiens
Background Reference 01
Hashimoto, T., et al., (1997) Eur. J. Neurosci. 9 (6), 1226-1235.
Other Product Names
GRM6, mGlu6, CSNB1B, GPRC1F, MGLUR6
Tested Applications
ELISA, WB
Protein ID
110611176
Physical Properties
Liquid
Frequently Asked Questions
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