SUV39H1 Antibody

SUV39H1, a human homolog of the Drosophila position effect variegation modifier Su (var) 3-9 and of the S. pombe silencing factor clr4, encodes a heterochromatic protein that transiently accumulates at centromeric positions during mitosis.This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SUV39H1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

SUV39H1 antibody can be used for detection of SUV39H1 by ELISA at 1:312500. SUV39H1 antibody can be used for detection of SUV39H1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.