PAX3 Antibody
Product Specifications
Background
PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2;13) (q35; q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.
NCBI Gene ID
5077
Swiss Prot
Q86UQ3
Accession Number
NP_852126
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Neuroscience, Apoptosis
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PAX3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
45 kDa
Applications Notes
PAX3 antibody can be used for detection of PAX3 by ELISA at 1:312500. PAX3 antibody can be used for detection of PAX3 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PAX3
NCBI Official Name
Paired box 3
NCBI Organism
Homo sapiens
Background Reference 01
Wachtel, M., et al., (2004) Cancer Res. 64 (16), 5539-5545.
Other Product Names
PAX3, WS1, WS3, CDHS, HUP2
Tested Applications
ELISA, WB
Protein ID
31563348
Physical Properties
Liquid
Frequently Asked Questions
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