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LHX3 Antibody

Product Specifications

Background

LHX3 is a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene.

NCBI Gene ID

8022

Swiss Prot

Q9UBR4

Accession Number

NP_835258

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LHX3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LHX3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

43 kDa, 44 kDa

Applications Notes

LHX3 antibody can be used for detection of LHX3 by ELISA at 1:1562500. LHX3 antibody can be used for detection of LHX3 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

LHX3

NCBI Official Name

LIM homeobox 3

NCBI Organism

Homo sapiens

Background Reference 01

Yaden, B.C., et al., (2006) Endocrinology 147 (1), 324-337.

Other Product Names

LHX3, LIM3, CPHD3, M2-LHX3

Tested Applications

ELISA, WB

Protein ID

30023847

Physical Properties

Liquid

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