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OTX2 Antibody

Product Specifications

Background

Homeobox protein OTX2 is a member of the bicoid sub-family of homeodomain-containing transcription factors. This protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined. This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.

NCBI Gene ID

5015

Swiss Prot

P32243-2

Accession Number

NP_068374

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OTX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store OTX2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=27-595

Calculated Molecular Weight

32 kDa

Applications Notes

OTX2 antibody can be used for detection of OTX2 by ELISA at 1:312500. OTX2 antibody can be used for detection of OTX2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

OTX2

NCBI Official Name

Orthodenticle homeobox 2

NCBI Organism

Homo sapiens

Background Reference 01

Sabunciyan, S., Am. J. Med. Genet. B Neuropsychiatr. Genet. 144 (8), 1083-1086.

Other Product Names

OTX2, MCOPS5, MGC45000, CPHD6

Tested Applications

ELISA, WB

Protein ID

11119420

Physical Properties

Liquid

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