HES1 Antibody

Product Specifications

Background

HES1 belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.

NCBI Gene ID

3280

Swiss Prot

Q14469

Accession Number

NP_005515

Host

Rabbit

Reactivity

Human, Mouse, Rat, Zebrafish

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HES1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer, Neuroscience

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1207 - Raji Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HES1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

30 kDa

Applications Notes

HES1 antibody can be used for detection of HES1 by ELISA at 1:62500. HES1 antibody can be used for detection of HES1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.