PIK3CB Antibody
Product Specifications
Background
Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al., 1993) .
NCBI Gene ID
5291
Swiss Prot
Q24JU2
Accession Number
NP_006210
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PIK3CB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PIK3CB antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
123 kDa
Applications Notes
PIK3CB antibody can be used for detection of PIK3CB by ELISA at 1:62500. PIK3CB antibody can be used for detection of PIK3CB by western blot at 5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PIK3CB
NCBI Official Name
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
NCBI Organism
Homo sapiens
Background Reference 01
Zhao, J.J., et al., (2005) Proc. Natl. Acad. Sci. U.S.A. 102 (51), 18443-18448.
Other Product Names
PIK3CB, PI3K, PIK3C1, P110BETA, PI3KBETA
Tested Applications
ELISA, WB
Protein ID
5453894
Physical Properties
Liquid
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