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PAX4 Antibody

Product Specifications

Background

PAX4 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box gene 4 is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing .- cells.

NCBI Gene ID

5078

Swiss Prot

O43316

Accession Number

NP_006184

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PAX4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

37 kDa

Applications Notes

PAX4 antibody can be used for detection of PAX4 by ELISA at 1:312500. PAX4 antibody can be used for detection of PAX4 by western blot at 0.5-2.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

PAX4

NCBI Official Name

Paired box 4

NCBI Organism

Homo sapiens

Background Reference 01

Holm, P., et al., (2004) Diabetes 53 (6), 1584-1591.

Other Product Names

PAX4, KPD, MODY9

Tested Applications

ELISA, WB, IHC

Protein ID

170784824

Physical Properties

Liquid

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