HOXD11 Antibody

HOXD11 belongs to the homeobox family. This family play an important role in morphogenesis in all multicellular organisms. The mouse Hoxd11 plays a role in forelimb morphogenesis.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HOXD11 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

HOXD11 antibody can be used for detection of HOXD11 by ELISA at 1:62500. HOXD11 antibody can be used for detection of HOXD11 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.