HCLS1 Antibody
Product Specifications
Background
HCLS1 Tyr phosphorylation catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets. This gene is a substrate for caspase cleavage during apoptosis.
NCBI Gene ID
3059
Swiss Prot
P14317
Accession Number
NP_005326
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HCLS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Signal Transduction, Immunology
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HCLS1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
54 kDa
Applications Notes
HCLS1 antibody can be used for detection of HCLS1 by ELISA at 1:312500. HCLS1 antibody can be used for detection of HCLS1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HCLS1
NCBI Official Name
Hematopoietic cell-specific Lyn substrate 1
NCBI Organism
Homo sapiens
Background Reference 01
Ruzzene, M., et al., (2002) Biochem. J. 364 (Pt 1), 41-47.
Other Product Names
HCLS1, HS1, CTTNL
Tested Applications
ELISA, WB, IHC
Protein ID
167234422
Physical Properties
Liquid
Curated Selection
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