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HCLS1 Antibody

Product Specifications

Background

HCLS1 Tyr phosphorylation catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets. This gene is a substrate for caspase cleavage during apoptosis.

NCBI Gene ID

3059

Swiss Prot

P14317

Accession Number

NP_005326

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HCLS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Signal Transduction, Immunology

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HCLS1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

54 kDa

Applications Notes

HCLS1 antibody can be used for detection of HCLS1 by ELISA at 1:312500. HCLS1 antibody can be used for detection of HCLS1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

HCLS1

NCBI Official Name

Hematopoietic cell-specific Lyn substrate 1

NCBI Organism

Homo sapiens

Background Reference 01

Ruzzene, M., et al., (2002) Biochem. J. 364 (Pt 1), 41-47.

Other Product Names

HCLS1, HS1, CTTNL

Tested Applications

ELISA, WB, IHC

Protein ID

167234422

Physical Properties

Liquid

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