AEBP1 Antibody
Product Specifications
Background
The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.
NCBI Gene ID
165
Swiss Prot
Q14113
Accession Number
NP_001120
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AEBP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store AEBP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=27-373
Calculated Molecular Weight
131 kDa
Applications Notes
AEBP1 antibody can be used for detection of AEBP1 by ELISA at 1:1562500. AEBP1 antibody can be used for detection of AEBP1 by western blot at 0.2-5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
AEBP1
NCBI Official Name
AE binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Layne, M.D., et al., (1998) J.Biol.Chem.273 (25), 15654-15660.
Other Product Names
AEBP1, ACLP
Tested Applications
ELISA, WB, IHC
Protein ID
53692189
Physical Properties
Liquid
Curated Selection
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