FOXN1 Antibody
Product Specifications
Background
Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.
NCBI Gene ID
8456
Swiss Prot
O15353
Accession Number
NP_003584
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOXN1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1207 - Raji Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FOXN1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
69 kDa
Applications Notes
FOXN1 antibody can be used for detection of FOXN1 by ELISA at 1:1562500. FOXN1 antibody can be used for detection of FOXN1 by western blot at 5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
FOXN1
NCBI Official Name
Forkhead box N1
NCBI Organism
Homo sapiens
Background Reference 01
Mecklenburg, L., et al., (2005) Exp. Dermatol. 14 (11), 797-810.
Other Product Names
FOXN1, WHN, RONU, FKHL20
Tested Applications
ELISA, WB
Protein ID
18201913
Physical Properties
Liquid
Curated Selection
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