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NFIC Antibody

Product Specifications

Background

Brg- or hBrm-associated factor (BAF) complexes, a chromatin-remodeling complex family of mammalian cells, facilitate transcriptional activity by remodeling nucleosome structure. Brg1 is the core subunit of Brg-associated factor complexes. BAF complexes can interact with NF1/CTF and RNAP II, and this interaction is closely dependent on the activation of gene transcription.

NCBI Gene ID

4782

Swiss Prot

P08651

Accession Number

NP_995315

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFIC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cell Cycle, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1219 - MCF7 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NFIC antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

55 kDa

Applications Notes

NFIC antibody can be used for detection of NFIC by ELISA at 1:1562500. NFIC antibody can be used for detection of NFIC by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

NFIC

NCBI Official Name

Nuclear factor I/C (CCAAT-binding transcription factor)

NCBI Organism

Homo sapiens

Background Reference 01

Hebert, S.L., Biochim. Biophys. Acta 1769 (11-12), 649-658 (2007) .

Other Product Names

NFIC, CTF, CTF5, MGC20153, NF-I, NFI

Tested Applications

ELISA, WB

Protein ID

45505151

Physical Properties

Liquid

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